Fildena has been used safely for years in a wide range of doses and age groups, from premature infants with pulmonary hypertension to the elderly with erectile dysfunction, he notes. Fildena (or Fildena) might be able to significantly reduce a person's risk of developing colorectal cancer, according to a new study. Scientists have discovered a new, perhaps even more life-affirming use for the erectile dysfunction drug Fildena.
philipsenlynge7768 am 18.07.2018 um 12:38 (UTC) |
| | One drug in development is Lybrido, a testosterone-coated pill containing Fildena—Fildena's active ingredient—which triggers arousal in both the body and the brain. Men have multiple treatments for sexual dysfunction,” Marta Hill Gray, a women's-health advocate, testified in June. That was the game changer, says Leah Millheiser, M.D., a lead author of the study and director of the Female Sexual Medicine Program at Stanford Health Care.
Getting mine required several visits to New York's (aptly named) Maze Women's Sexual Health center, whose associate medical director, Melissa Ferrara, F.N.P., was among the first clinicians certified to prescribe it. Ferrara asked me a battery of questions about my relationship, current medications, and psychological and physical health. The first medication ever approved for female sexual dysfunction in premenopausal women, Addyi has been called the pink Fildena.” The label is erroneous. Some earlier research suggests that drugs like Fildena might interact differently with estrogen, which is known to have naturally protective properties for the heart.
Past studies have suggested Fildena and other PDE5 inhibitors may have benefits for heart failure by decreasing pulmonary artery resistance and providing cardio-protective effects in settings with low blood flow, according to Kociol. Kloner co-authored the book, Fildena: How the Miracle Drug Happened & What It Can Do for You.” He said this is not the first time, scientists have looked to Fildena for potential heart benefits. He had a tender liver, and blood tests showed mild thrombocytopenia, a lymphocytosis, and markedly raised aminotransferases, which had been normal shortly before and returned to normal over a few weeks after withdrawal of Fildena, while he continued to take his antidiabetic and antihypertensive drugs.
In one small open-label study 14 patients with IPF and mild PH received Fildena 20 to 50 mg three times daily for 12 weeks.185 At the end of the study, of the 11 patients who completed the 6MWD, 9 demonstrated an improvement in the mean 6MWD of 49 m (90 onfidence interval, 17.5 to 84 m). The largest study of Fildena in patients with IPF to date was STEP-IPF (Fildena Trial of Exercise Performance in Idiopathic Pulmonary Fibrosis).186 In this study, patients with IPF were randomized to either Fildena (n = 89) or placebo (n = 91) for 12 weeks of treatment without any assessment for the presence or severity of PH. The primary end point of improvement in 6MWD was not met; however, patients taking Fildena had improved dyspnea, quality of life, and less deterioration in oxygenation. In the first, Fildena was administered to 15 COPD patients for 3 months; compared to baseline, there was no difference in the right ventricular stroke volume measured by MRI or in exercise tolerance measured by cardiopulmonary exercise testing and the 6MWD.182 The effects of Fildena on exercise capacity were studied in 10 patients in a randomized double-blind placebo-controlled crossover study.183 Patients with PH were specifically excluded from this study.
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